E00: Congenital iodine-deficiency syndrome

E00 refers to Congenital iodine-deficiency syndrome, a category of thyroid-related disorders often linked to iodine imbalance, autoimmune dysfunction, congenital anomalies, or thyroid inflammation. These conditions impact metabolism, growth, neurological function, and overall endocrine health.

Symptoms

• Fatigue – Common in hypothyroid or iodine-deficient conditions
• Goiter – Thyroid gland enlargement seen in iodine disorders and thyroiditis
• Weight changes – Weight gain (hypothyroidism) or loss (hyperthyroidism)
• Heat or cold intolerance – Seen in hyper- or hypothyroid states
• Hair thinning or dry skin – Typical of thyroid hormone imbalance
• Heart palpitations or anxiety – Seen in hyperthyroidism
• Developmental delay – Present in congenital thyroid disorders

Diagnosis

Diagnosis of Congenital iodine-deficiency syndrome includes thyroid function tests (TSH, free T4, T3), thyroid antibody panels, neck ultrasound, radioactive iodine uptake tests, and fine-needle aspiration if nodules are found. Early detection helps prevent complications, especially in congenital or subclinical cases.

ICD10 Code Usage

ICD10 code E00 is used by endocrinologists, pediatricians, general practitioners, and internal medicine physicians to document thyroid diseases. It supports accurate tracking, hormonal therapy management, prenatal and neonatal screening, and insurance billing.

Related Codes

• E01 – Iodine-deficiency related thyroid disorders and allied conditions
• E02 – Subclinical iodine-deficiency hypothyroidism
• E03 – Other hypothyroidism
• E04 – Other nontoxic goiter
• E05 – Thyrotoxicosis [hyperthyroidism]
• E06 – Thyroiditis
• E07 – Other disorders of thyroid

FAQs

Q1: What is ICD10 code E00?
A: This code documents Congenital iodine-deficiency syndrome, a type of thyroid disorder related to iodine deficiency, autoimmune disease, or gland dysfunction.

Q2: What causes these thyroid disorders?
A: Common causes include iodine deficiency, autoimmune thyroiditis (Hashimoto's or Graves'), congenital defects, and infections.

Q3: Are they treatable?
A: Yes. Management includes thyroid hormone replacement, antithyroid medications, iodine supplementation, or surgery in some cases.

Q4: Who is most affected?
A: Women, older adults, individuals in iodine-deficient regions, and people with autoimmune conditions are most at risk.

Q5: Can they be prevented?
A: Some can be prevented with adequate iodine intake, newborn screening, and early treatment of thyroid inflammation.

Conclusion

ICD10 code E00 ensures proper classification and monitoring of Congenital iodine-deficiency syndrome. Accurate diagnosis and coding aid in managing hormonal therapy, guiding public health nutrition strategies, and preventing complications of untreated thyroid disease.