N01: Rapidly progressive nephritic syndrome

N01 refers to Rapidly progressive nephritic syndrome, a group of glomerular disorders affecting kidney function through inflammation, protein leakage, hematuria, or hereditary structural defects, potentially leading to chronic kidney disease if untreated.

Symptoms

• Hematuria (blood in urine) – Hallmark of nephritic syndromes (N00, N01, N03)
• Proteinuria (protein in urine) – Prominent in nephrotic syndrome (N04)
• Edema (swelling) – Due to low protein levels (N04, N06)
• Hypertension – Common in glomerular diseases
• Progressive renal insufficiency – Seen in chronic forms (N03, N07)

Diagnosis

Diagnosis of Rapidly progressive nephritic syndrome involves urinalysis (checking for protein and blood), kidney function tests (serum creatinine, eGFR), imaging (renal ultrasound), and kidney biopsy for histological evaluation, particularly when morphology-specific diagnoses (N06) are needed.

ICD10 Code Usage

ICD10 code N01 is used by nephrologists, internists, pediatric nephrologists, and primary care physicians to diagnose, track, and manage glomerular diseases and guide therapeutic decisions like immunosuppressive therapy or preparation for dialysis in severe cases.

Related Codes

• N00 – Acute nephritic syndrome
• N02 – Recurrent and persistent hematuria
• N03 – Chronic nephritic syndrome
• N04 – Nephrotic syndrome
• N05 – Unspecified nephritic syndrome
• N06 – Isolated proteinuria with specified morphological lesion
• N07 – Hereditary nephropathy, not elsewhere classified
• N08 – Glomerular disorders in diseases classified elsewhere

FAQs

Q1: What is ICD10 code N01?
A: It refers to Rapidly progressive nephritic syndrome, encompassing disorders of the kidney's glomeruli resulting in hematuria, proteinuria, edema, and/or kidney dysfunction.

Q2: What distinguishes nephritic from nephrotic syndromes?
A: Nephritic syndromes (N00, N01, N03) primarily involve inflammation and hematuria, whereas nephrotic syndrome (N04) involves massive protein loss and edema without prominent hematuria.

Q3: What is isolated proteinuria (N06)?
A: Presence of significant protein in urine without the typical systemic signs of nephrotic syndrome, often diagnosed via biopsy.

Q4: What are hereditary nephropathies (N07)?
A: Genetic kidney diseases like Alport syndrome that affect glomerular structure and function.

Q5: How are glomerular disorders treated?
A: Treatments vary but may include corticosteroids, immunosuppressants, antihypertensives, diuretics, dietary modifications, and renal replacement therapies in advanced cases.

Conclusion

ICD10 code N01 provides a clear framework for diagnosing and managing Rapidly progressive nephritic syndrome, supporting early detection, proper classification, and effective treatment to preserve renal function and prevent complications like chronic kidney disease.